Depression mediations are frequently grouped according to how they work in the body or their chemical structure.

Some groups of antidepressants that are popular today are:

• SSRIs - Selective Serotonin Reuptake Inhibitors
• SNRI - Serotonin-Norepinephrine Reuptake Inhibitors
• Tri-cyclic antidepressants
• MAOIs - (Irreversible) Monoamine Oxidase Inhibitors
• RIMAs - Reversible Monoamine Oxidase Inhibitors
• NDRIs - Norepinephrine-Dopamine Reuptake Inhibitors